Acute Myeloid Leukemia

START YOUR TREATMENT OFF RIGHT WITH VENCLEXTA

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Getting started

VENCLEXTA is an oral medicine taken by mouth each day. VENCLEXTA is taken in combination with azacitidine, or decitabine, or low-dose cytarabine. Your healthcare provider can advise which VENCLEXTA combination regimen may be appropriate for you.

You will start taking VENCLEXTA at a low dose and gradually increase to a higher dose—this is called a “ramp-up period.” The ramp-up dosing will depend on which regimen you and your healthcare provider have chosen. Once you’re at the full dose, continue to take VENCLEXTA as prescribed by your healthcare provider.

See important information about getting started with VENCLEXTA.

Brochure icon

VENCLEXTA Patient Brochure

For more information about dosing, see the VENCLEXTA Patient Brochure.

VENCLEXTA oral dosing schedule

Day 1

One 100 mg tablet of VENCLEXTA

Take 100 mg of VENCLEXTA

and your healthcare provider will start you on azacitidine 75 mg/m2 (IV or SC), or decitabine 20 mg/m2 (IV), or cytarabine 20 mg/m2 (SC).

Day 2

One 100 mg tablet of VENCLEXTA One 100 mg tablet of VENCLEXTA

Take 200 mg of VENCLEXTA

in combination with azacitidine 75 mg/m2 (IV or SC), or decitabine 20 mg/m2 (IV), or cytarabine 20 mg/m2 (SC) as determined by your healthcare provider.

Day 3

One 100 mg tablet of VENCLEXTA One 100 mg tablet of VENCLEXTA One 100 mg tablet of VENCLEXTA One 100 mg tablet of VENCLEXTA

Take 400 mg of VENCLEXTA

in combination with azacitidine 75 mg/m2 (IV or SC), or decitabine 20 mg/m2 (IV), or cytarabine 20 mg/m2 (SC) as determined by your healthcare provider.

Day 4 and beyond (28-day cycle)

In combination with azacitidine or decitabine:

 

One 100 mg tablet of VENCLEXTAOne 100 mg tablet of VENCLEXTAOne 100 mg tablet of VENCLEXTAOne 100 mg tablet of VENCLEXTA
 

Take 400 mg of VENCLEXTA

in combination with azacitidine 75 mg/m2 (IV or SC) on Days 1-7, or decitabine 20 mg/m2 (IV) on Days 1-5 of each 28-day cycle as determined by your healthcare provider.

OR

In combination with low-dose cytarabine:

 

One 100 mg tablet of VENCLEXTAOne 100 mg tablet of VENCLEXTAOne 100 mg tablet of VENCLEXTAOne 100 mg tablet of VENCLEXTAOne 100 mg tablet of VENCLEXTAOne 100 mg tablet of VENCLEXTA
 

Take 600 mg of VENCLEXTA

in combination with cytarabine 20 mg/m2 (SC) on Days 1-10 of each 28-day cycle as determined by your healthcare provider.

For illustrative purposes only; pills are not actual size.

Intravenous (IV) means within a vein. In this type of injection, the medication is injected directly into the vein.

Subcutaneous (SC) means under the skin. In this type of injection, the medication is injected into the tissue layer between the skin and the muscle.

VENCLEXTA CALENDAR

Keep track of when you take your medication

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Learn more about treating AML with VENCLEXTA