Take VENCLEXTA exactly as your doctor tells you to take it. Do not change your dose of VENCLEXTA or stop taking VENCLEXTA unless your doctor tells you to. When you first take VENCLEXTA, you may need to take it at the hospital or clinic to monitor for tumor lysis syndrome (TLS).

VENCLEXTA drink water icon
  • Drink plenty of water when taking VENCLEXTA to help reduce your risk of getting TLS. Drink 6 to 8 glasses (about 56 ounces total) of water each day, starting 2 days before your first dose, on the day of your first dose of VENCLEXTA, and each time your dose is increased
  • VENCLEXTA is an oral medicine you should take once a day with a meal and water at about the same time each day
  • Swallow VENCLEXTA tablet(s) whole. Do not chew, crush, or break the tablets 
  • Do not drink grapefruit juice, eat grapefruit, Seville oranges (often used in marmalades), or starfruit while you are taking VENCLEXTA. These products may increase the amount of VENCLEXTA in your blood
  • If you vomit after taking VENCLEXTA, do not take an extra dose that day. Take the next dose at the usual time the following day

What if I miss a dose?

Missing a VENCLEXTA dose image

Store VENCLEXTA at or below 86°F (30°C).