Previously Untreated CLL/SLL


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Serious side effects

Side effects can be managed with your healthcare provider. Each person responds differently to VENCLEXTA. Side effects are a real possibility, and some can be very serious. These include:

Some people may experience other side effects.

Common side effects

Common side effects that occurred with VENCLEXTA when used in combination with GAZYVA or rituximab or alone include:

White blood cells icon Low white blood cell counts
Platelet icon Low platelet counts
Red blood cells icon Low red blood cell counts
Toilet paper icon Diarrhea
Nauseous person icon Nausea
Upper respiratory icon Upper respiratory tract infection
Cough medicine icon Cough
Muscle and joint icon Muscle and joint pain
Tired person icon Tiredness
Swollen ankle icon Swelling of arms, legs, hands, and feet

Your healthcare provider may delay or decrease your dose or stop treatment if you have side effects. Don’t stop or change your dose unless directed by your healthcare provider.

VENCLEXTA may cause fertility problems in males. This may affect your ability to father a child. Talk to your healthcare provider if you have concerns about fertility.

These are not all the possible side effects of VENCLEXTA. For more information, ask your healthcare provider or pharmacist. You are encouraged to report negative side effects of prescription drugs to the FDA.

Helpful tips

It's important to take care of yourself while on treatment. The activities below can help you practice a healthy lifestyle:

Dumbbell icon Exercise
Meditation icon Meditation
Accupunture icon Acupuncture
Candle and stone icon Therapeutic massage
Yoga mat and water bottle icon Yoga

Check with your healthcare provider before practicing any of the above activities.

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Because the VENCLEXTA regimens are taken for a fixed amount of time, there is no additional VENCLEXTA regimen exposure after completing treatment

Full Dosing Schedule


Download questions to ask your doctor about CLL/SLL and your treatment goals

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Learn more about VENCLEXTA