VENCLEXTA is an oral medicine that you take once a day that works differently from other drugs. VENCLEXTA targets a specific protein in your body called BCL-2.

When normal cells are damaged or old, your body tells them to self-destruct. This natural process is called apoptosis.

  • When you have CLL, BCL-2 may build up and prevent cancer cells from self-destructing naturally
  • VENCLEXTA targets BCL-2 in order to help restore the process of apoptosis. Through apoptosis, your body allows cancer cells and normal cells to self-destruct

Select Important Safety Information

VENCLEXTA can cause serious side effects, including:

  • Tumor lysis syndrome: See What is Tumor Lysis Syndrome? for information on TLS
  • Low white blood cell count (neutropenia). Low white blood cell counts are common with VENCLEXTA, but can also be severe. Your doctor will do blood tests to check your blood counts during treatment with VENCLEXTA. Tell your doctor right away if you have a fever or any signs of an infection